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Thrombate® III
Manufacturer:
Grifols
Generic Name:
Antithrombin III (Human)
Indications:
- Thrombate®
III is indicated for
the treatment of patients with
hereditary antithrombin III
deficiency in connection with
surgical or obstetrical
procedures or when they suffer
from thromboembolism.
- Subjects with AT-III
deficiency should be informed
about the risk of thrombosis in
connection with pregnancy and
surgery and about the
inheritance of the disease.
- The diagnosis of hereditary
antithrombin III (AT-III)
deficiency should be based on a
clear family history of venous
thrombosis as well as decreased
plasma AT-III levels, and the
exclusion of acquired
deficiency.
- AT-III in
plasma may be measured by
amidolytic assays using
synthetic chromogenic
substrates, by clotting assays,
or by immunoassays. The latter
does not detect all hereditary
AT-III deficiencies.
- The AT-III level in neonates
of parents with hereditary
AT-III deficiency should be
measured immediately after
birth. (Fatal neonatal
thromboembolism, such as aortic
thrombi in children of women
with hereditary antithrombin III
deficiency, has been reported)
- Plasma levels of AT-III are
lower in noenates than adults,
averaging approximately 60% in
normal term infants. AT-III
levels in premature infants may
be much lower. Low plasma
AT-III levels, especially in a
premature infant, therefore, do
not necessarily indicate
hereditary deficiency. It is
recommended that testing and
treatment with Thrombate® III of
neonates be discussed with an
expert on coagulation.
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Available Sizes |
Size |
NDC Numbers |
PI |
MSDS |
| Thrombate® III
|
500 unit vial |
13533-0603-20 |
PI |
MSDS |
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| Clinical
Data:
For any questions or for
further information regarding
Thrombate® III,
Antithrombin
(Human)-AT-III, clinical
pharmacology, additional
indications and usages,
contraindications, warnings,
precautions, adverse reactions,
dosage, administration and/or
storage of this product, please
contact BDI Pharma or call
1-800-948-9834. |
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