Injectables - C1-Esterase Inhibitor
Hereditary Angioedema (HAE) is a very rare and
potentially life-threatening genetic condition that occurs in about
1 in 10,000 to 1 in 50, 000 people. HAE symptoms include
episodes of edema (swelling) in various body parts including the
hands, feet, face and airway.
In addition, patients often
have bouts of excruciating abdominal pain, nausea and vomiting that
is caused by swelling in the intestinal wall. Airway swelling
is particularly dangerous and can lead to death by asphyxiation.
HAE patients have a defect in the gene that controls a blood
protein called C1 Inhibitor. The genetic defect results in
production of either inadequate or non-functioning C1-Inhibotor
protein. Normal C1-INhibiotr helps to regulate the complex
biochemical interactions of blood-based systems involved in disease
fighting, inflammatory response and coagulation. Because
defective C1-Inhibitor does not adequately perform its regulatory
function, a biochemical imbalance can occur and produce unwanted
peptides that induce the capillaries to release fluids into the
surrounding tissue, thereby causing edema.
C1-Esterase Inhibitor |
|
| |
|
| |
|
| Additional information about C1-Protease Inhibitors, Hereditary Angioedema, or other products may be found in our
Clinical Resources section. If you need additional information regarding any of these products please
contact BDI Pharma or call 1- 800-948-9834. |
| |
|
| |
|
| |
|
| |
|
| |
|
| |
|
| |
|
| |
|
| |
|
| |
|
| |
|
| |
|
| |
|
| |
|
| |
|
| |
|
| |
|