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Titlesort descending Definition
HAE See: Hereditary Angioedema
Heat Treated Viral inactivation process that uses heat up to 80 degrees C.
Hemarthrosis Accumulation of blood in a joint or joint cavity; extreme swelling often results. This condition is a common symptom of hemophilia and can lead to pain and stiffness of the joints. Occurrence of hemarthrosis in hemophiliacs may be lowered through prophylactic dosage of the appropriate coagulation factor.
Hematology The study of blood-producing tissues, and diagnosis and treatment of disorders of blood and blood-producing tissues.
Hematuria Presence of blood in the urine.
Hemin Injection Hemin is an iron-containing porphyrin used in the management of porphyria attacks, particularly in acute intermittent porphyria.
Hemoglobin The component of red blood cells that carries oxygen from the lungs to the tissues of the body.
Hemolysis The rupture of red blood cells.
Hemolytic Anemia A low red blood cell count resulting from any medical condition which causes red blood cells to burst.
Hemolytic Disease of the Newborn (HDN) This is a potentially severe condition affecting newborns. If a mother has developed antibodies to her fetus' blood type, the mother's blood attacks the fetus' blood, causing the red blood cells to burst. The baby is born anemic, jaundiced, and with an enlarged liver and spleen. This condition is most easily prevented by careful prenatal care in which the mother's blood is prevented from forming the antibodies against the fetus' blood.
Hemophilia Disease in which the blood does not clot properly. Any of several hereditary disorders in which blood takes an abnormally long time to coagulate due to a deficiency or abnormality in one of the blood coagulation factors. It is a recessive, X-linked trait which manifests almost exclusively in males. Females can carry the gene without having the disease; each son of a female carrier has a 50% chance of receiving the gene and having hemophilia. There is no cure for hemophilia. It is treated through the administration of the deficient factor.
Hemophilia A Disease in which the blood does not clot properly due to a deficiency of blood coagulation Factor VIII. Treated by administering Factor VIII. The disease is an X-linked trait and occurs mostly in males.
Hemophilia B Disease in which the blood does not clot properly due to a deficiency of blood coagulation Factor IX. Also known as Christmas Disease. Treated by administering Factor IX. The disease is an X-linked trait and occurs mostly in males. It is so named because the first patient with the disease to be studied in great detail was named Christmas.
Hemostasis The process which stops bleeding at an injury's site.
Hepatitis Inflammation of the liver. It may be caused by a variety of agents, including viral infections, bacterial invasion, and physical or chemical agents. It is characterized by jaundice, fever, liver enlargement, and abdominal pain.
Hereditary Angioedema (HAE) Deficiency of C1 esterase inhibitor, which causes attacks of rapid swelling in the hands, feet, limbs, face, intestinal tract, larynx or trachea. Attacks which obstruct airways can be fatal.
High-Titer Immune Globulin See: Hyper-Immune
HIV Human Immunodeficiency Virus. Acute infectious manifestations, neurological disorders, and immunologic abnormalities linked to the acquired immunodeficiency syndrome (AIDS).
Humoral Immunity Immune defense in which antibodies are produced by B-lymphocytes and circulate as soluble proteins in blood in lymph (or humors0. This is in comparison to cell-medicated immunity in which the T-cells come in close proximity to their victim cells). Humoral immunity is acquired; antibodies are produced by B- cells only in response to specific antigens.
Hyper-immune In reference to plasma, it refers to a plasma product with a very high titer of a specific antibody. Administration of this plasma results in the immune system being much more reactive to the specific antigen than it normally would be.
Hypersensitivity An abnormal, exaggerated immune response that may be either immediate (due to antibodies of the IgE class, e.g. an allergy to ragweed) or delayed (due to cell-mediated immunity, e.g. a transplant rejection). It may result in tissue damage.
Hypogammaglobulinemia Deficiency of immunoglobulins, resulting in a weakened immune system and an increased susceptibility to infection. Treatment includes administration of intravenous immune globulin (IVIG).