A | B | C | D | E | F | G | H | I |
J |
K | L | M | N | O | P |
Q |
R | S | T |
U |
V | W | X |
Y |
Z |
Titlesort descending Definition
Parvovirus B19 A very small, non-enveloped virus that causes fifth disease, usually benign, non-febrile disease. Infection in immunocompromised patients may result in complications and may lead to death.
Passive Immunity Immunity acquired through the transfer of antibodies from another person or animal. This may occur naturally, as from mother to fetus through the placenta or to infant through breast-feeding, or artificially through injection of immune globulin.
Pasteurization Process of heating liquids to destroy harmful or undesirable microorganisms.
Pathogen An agent of disease. The term pathogen most commonly refers to infectious organisms. These include bacteria such as staph, viruses such as HIV, and fungi such as yeast.
PCC See: Prothrombin Complex Concentrate
pepsin Pepsin is a digestive enzyme used by the stomach to digest food. It is also useful in the viral safety processing of plasma products when used in the presence of a lower pH solution.
Perinatal Transmission The transmission of a pathogen from mother to baby before, during, or after the birth process.
PID See: Primary Immune Deficiency
Plasma The clear, protein rich, fluid component of blood, containing dissolved solutes, and minus the red blood cells. Clotting factors are found in plasma. Note that plasma differs from serum in that it contains fibrin and other soluble clotting elements. It can be sterilized and administered intravenously.
Plasma Protein Fraction (PPF) PPF, also known as human albumin serum, is a standard sterile preparation of serum albumin and globulin obtained by fractionating blood, serum, or albumin from healthy human donors. It is sterilized and tested. It is used as a blood volume expander, in the treatment of burns where albumin is lost rapidly, and in the treatment of hypoalbuminaemic patients with edema where diuretics have failed.
Plasmapheresis The process in which plasma is removed from donated blood and the remaining components, mostly red blood cells, are returned to the donor.
Platelets A small, disk-shaped blood cell with no nucleus that circulates in the blood and participates (together with fibrin) in forming blood clots. When an injury occurs, platelets adhere to one another and the edges of the injury to form a plug to cover the area. Platelets are derived from megakaryocytes. Also called a thrombocyte.
PPF See: Plasma Protein Fraction
Primary Humoral Immunodeficiency See: Primary Immune Deficiency
Primary Immune Deficiency (PID) An immune deficiency arising from intrinsic defects in the cells of the immune system (as opposed to secondary, acquired deficiencies caused by infection). PID's are often caused by inherited genetic defects.
Product Half Life The time that it takes for a medication's level and effectiveness in the body to reach half that of initial administration as it is metabolized or inactivated by the body. It is used as a measure of effectiveness in treatment and is important in determining the drug dosage amount and frequency.
Product Shelf Life The time a product retains effectiveness after its date of manufacture.
Prophylaxis Preventative treatment measures. In factor usage, it is the scheduled infusion of the necessary factor to maintain high levels in the blood stream and prevent most bleeds.
Protease Inhibitor Antiviral drugs that act by inhibiting the virus' protease enzyme, thereby preventing viral replication.
Prothrombin Blood Coagulation Factor II, a protein in the blood that aids in clotting. Prothrombin is converted to thrombin through a series of reactions in response to bleeding. A chemical substance existing in circulating blood that, through the medium of thrombokinase, interacts with calcium salts to produce thrombin. It is formed and stored in the liver.
Prothrombin Complex Concentrate (PCC) PCC contains blood coagulation factors II, VII, IX and X, proteins C and S, and small amounts of activated coagulation factor.
Pruritis Itching.